Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322431 | 1.00 | EPHX1 (0.46) | EPHX1USP30HPGDRECQLPTPN2 | |
| SCHEMBL25321057 | 1.00 | EPHX1 (0.46) | EPHX1USP30HPGDRECQLPTPN2 | |
| SCHEMBL12280117 | 1.00 | EPHX1 (0.46) | EPHX1USP30HPGDRECQLPTPN2 | |
| SCHEMBL5644308 | 0.85 | EPHX1 (0.45) | EPHX1USP30HPGDRECQLPTPN2 | |
| SCHEMBL1457410 | 0.83 | EPHX1 (0.55) | EPHX1USP30HDAC4HDAC6ALDH1A1 | |
| SCHEMBL24817359 | 0.83 | EPHX1 (0.55) | EPHX1USP30HDAC4HDAC6ALDH1A1 | |
| SCHEMBL6865392 | 0.83 | EPHX1 (0.55) | EPHX1USP30HDAC4HDAC6ALDH1A1 | |
| SCHEMBL19540973 | 0.81 | EPHX1 (0.48) | EPHX1USP30HPGDRECQLPTPN2 | |
| SCHEMBL22626896 | 0.81 | EPHX1 (0.46) | EPHX1USP30HPGDRECQLPTPN2 | |
| SCHEMBL22624428 | 0.81 | EPHX1 (0.46) | EPHX1USP30HPGDRECQLPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |