Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.85 |
| ▸ | JAK1 | P23458 | 3/20 | 0.77 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.77 |
| ▸ | RET | P07949 | 2/20 | 0.77 |
| ▸ | TYK2 | P29597 | 2/20 | 0.77 |
| ▸ | FLT3 | P36888 | 2/20 | 0.77 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.77 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.77 |
| ▸ | STK4 | Q13043 | 2/20 | 0.77 |
| ▸ | STK3 | Q13188 | 2/20 | 0.77 |
| ▸ | MARK2 | Q7KZI7 | 2/20 | 0.77 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.77 |
| ▸ | RPS6KA6 | Q9UK32 | 2/20 | 0.77 |
| ▸ | JAK2 | O60674 | 2/20 | 0.77 |
| ▸ | JAK3 | P52333 | 2/20 | 0.77 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.77 |
| ▸ | CSF1R | P07333 | 1/20 | 0.77 |
| ▸ | FLT4 | P35916 | 1/20 | 0.77 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.77 |
| ▸ | ITK | Q08881 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL735252 | 0.92 | SYK (1.00) | SYKJAK1CHEK1RETTYK2 | |
| SCHEMBL736742 | 0.90 | SYK (1.00) | SYKJAK1CHEK1RETTYK2 | |
| SCHEMBL735871 | 0.90 | SYK (1.00) | SYKJAK1JAK2JAK3 | |
| SCHEMBL737456 | 0.88 | SYK (1.00) | SYK | |
| SCHEMBL734995 | 0.88 | SYK (1.00) | SYKJAK1CHEK1RETTYK2 | |
| Cerdulatinib SCHEMBL736734 | 0.87 | SYK (1.00) | SYKJAK1CHEK1RETTYK2 | |
| SCHEMBL17083658 | 0.87 | SYK (0.75) | SYKJAK1CHEK1RETTYK2 | |
| SCHEMBL735847 | 0.87 | SYK (1.00) | SYK | |
| SCHEMBL737987 | 0.87 | SYK (1.00) | SYK | |
| SCHEMBL22278302 | 0.86 | SYK (0.98) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713309-B2 | Solid forms of Cerdulatinib | ALEXION PHARMACEUTICALS, INC. (US) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713309-B2 | Solid forms of Cerdulatinib | CLK1, CLK2, DCLK1 | SYK 1096/4885JAK1 14/4885CHEK1 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.