Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25916841 | 0.74 | POLB (0.40) | POLBARKDM4EMEN1KMT2A | |
| SCHEMBL25916805 | 0.74 | POLB (0.40) | POLBARKDM4EMEN1KMT2A | |
| SCHEMBL25917060 | 0.71 | GAA (0.45) | POLBGAAARKDM4EMEN1 | |
| SCHEMBL18256147 | 0.70 | GAA (0.43) | POLBGAAKDM4EMAPTHSD17B10 | |
| SCHEMBL25916968 | 0.69 | AR (0.41) | ARKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL25916855 | 0.69 | POLB (0.40) | POLBARKDM4EMEN1KMT2A | |
| SCHEMBL25916870 | 0.69 | POLB (0.40) | POLBARKDM4EMEN1KMT2A | |
| SCHEMBL17971479 | 0.68 | HPGD (0.43) | ARKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL1540434 | 0.68 | HTT (0.51) | MAPTHSD17B10ALDH1A1 | |
| SCHEMBL10685599 | 0.68 | HSD17B10 (0.40) | GAAKDM4EMAPTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141262-A1 | BAX ACTIVATORS AND USE THEREOF | IPSEN PHARMA S.A.S. (FR) | 2023-07-27 | — | — | WO | disclosed |