Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25916855 | 0.83 | POLB (0.40) | POLBARPLA2G1BATG4BALDH1A1 | |
| SCHEMBL25916967 | 0.74 | POLB (0.41) | POLBARALDH1A1KDM4EHPGD | |
| SCHEMBL25916841 | 0.73 | POLB (0.40) | POLBARALDH1A1KDM4EHPGD | |
| SCHEMBL25916870 | 0.71 | POLB (0.40) | POLBARALDH1A1KDM4EHPGD | |
| SCHEMBL11321180 | 0.70 | PLA2G1B (0.56) | PLA2G1BATG4BALDH1A1KDM4EHPGD | |
| SCHEMBL11589418 | 0.68 | ALDH1A1 (0.43) | POLBALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL25916551 | 0.68 | ALDH1A1 (0.44) | POLBALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL25917061 | 0.66 | AR (0.41) | ARALDH1A1KDM4EHPGDSCN2A | |
| SCHEMBL11018031 | 0.66 | AR (0.40) | ARALDH1A1KDM4EHPGDSCN2A | |
| SCHEMBL25916968 | 0.66 | AR (0.41) | ARALDH1A1KDM4EHPGDSCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141262-A1 | BAX ACTIVATORS AND USE THEREOF | IPSEN PHARMA S.A.S. (FR) | 2023-07-27 | — | — | WO | disclosed |