Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 11/20 | 0.42 |
| ▸ | CDK1 | P06493 | 11/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 11/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 11/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.38 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24122166 | 0.76 | CCR1 (0.46) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL15070856 | 0.70 | CCNB2 (0.39) | CCNB2CDK1CCNB1CCNB3CCR1 | |
| SCHEMBL12203219 | 0.70 | CCR1 (0.65) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL25519645 | 0.68 | CCR1 (0.46) | CCR1CCR5CCR8CDK5PSMD14 | |
| SCHEMBL3231063 | 0.67 | CCNB2 (0.51) | CCNB2CDK1CCNB1CCNB3CCNE1 | |
| SCHEMBL24122165 | 0.63 | CCR1 (0.45) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL11804205 | 0.62 | CCR1 (0.54) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL3156717 | 0.62 | CCR1 (0.54) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL15070854 | 0.62 | GRM4 (0.36) | CCNB2CDK1CCNB1CCNB3CYP1A2 | |
| SCHEMBL13193188 | 0.60 | CCR1 (0.37) | CCNB2CDK1CCNB1CCNB3CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137034-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2023-07-20 | — | — | WO | disclosed |