Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 3/20 | 0.35 |
| ▸ | NOS2 | P35228 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13193188 | 0.87 | CCR1 (0.37) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL12203219 | 0.81 | CCR1 (0.65) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL12032781 | 0.79 | SLC40A1 (0.37) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL12131703 | 0.76 | HTR1A (0.53) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL12533426 | 0.76 | PSMD14 (0.62) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL13394546 | 0.76 | CCR1 (0.33) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL26400675 | 0.74 | HTR1A (0.39) | HTR1AADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL12992620 | 0.74 | CCR1 (0.38) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL12992615 | 0.74 | CCR1 (0.38) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL23132774 | 0.71 | PDPK1 (0.41) | CCR1CCR5CCR8PSMD14COPS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |