⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9555934 | 0.89 | SLC1A1 (0.36) | — | |
| SCHEMBL9748876 | 0.84 | GSR (0.37) | — | |
| SCHEMBL2078990 | 0.82 | GSR (0.35) | — | |
| SCHEMBL30121454 | 0.81 | NLN (0.33) | — | |
| SCHEMBL11028922 | 0.79 | CYP1A2 (0.32) | — | |
| SCHEMBL7586770 | 0.79 | CYP3A4 (0.30) | — | |
| Histidine SCHEMBL2763245 | 0.78 | SLC7A5 (0.43) | — | |
| Histidine SCHEMBL8027991 | 0.78 | SLC7A5 (0.43) | — | |
| Histidine SCHEMBL1801721 | 0.78 | SLC7A5 (0.43) | — | |
| Histidine SCHEMBL1136528 | 0.78 | SLC7A5 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865857-B2 | Medical device with predefined activated cellular integration | SOFRADIM PRODUCTION (FR) | 2014-10-21 | — | — | US | claimed |
| US-4732155-A | Implantable chemoattractant system | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1988-03-22 | — | — | US | claimed |
| US-9586989-B1 | Non-toxic skin cancer therapy with copper peptides | SKIN BIOLOGY, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-8865857-B2 | Medical device with predefined activated cellular integration | SOFRADIM PRODUCTION (FR) | 2014-10-21 | — | — | US | disclosed |
| US-20130143976-A1 | MEDICAL DEVICE WITH PREDEFINED ACTIVATED CELLULAR INTEGRATION | SOFRADIM PRODUCTION (FR) | 2013-06-06 | — | — | US | disclosed |
| EP-2588153-A2 | MEDICAL DEVICE WITH PREDEFINED ACTIVATED CELLULAR INTEGRATION | Sofradim Production (FR) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012001532-A2 | MEDICAL DEVICE WITH PREDEFINED ACTIVATED CELLULAR INTEGRATION | SOFRADIM PRODUCTION (FR) | 2012-01-05 | — | — | WO | disclosed |
| EP-0438600-B2 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6156555-A | Method of preparing an enzyme participating in C-terminal amidation | SHISEIDO COMPANY LTD. (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0666318-B1 | Enzyme participating in c-terminal amidation, and method of preparing same and use thereof | SHISEIDO CO LTD (JP) | 2000-11-29 | — | — | EP | disclosed |
| US-5871995-A | Purified enzymes participating in C-terminal amidation | SHISEIDO COMPANY, LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0438600-B1 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO CO LTD (JP) | 1996-02-07 | — | — | EP | disclosed |
| EP-0666318-A1 | Enzyme participating in c-terminal amidation, and method of preparing same and use thereof | SHISEIDO COMPANY LIMITED (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5354675-A | Amidation of glycine | SHISEIDO COMPANY LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0447547-B1 | C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE | SHISEIDO CO LTD (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5252559-A | A stimulate mixture of a tripeptides and carrier | THE PROCTER & GAMBLE COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| US-5252559-A | A stimulate mixture of a tripeptides and carrier | THE PROCTER & GAMBLE COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0447547-A1 | C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE | SHISEIDO COMPANY LIMITED (JP) | 1991-09-25 | — | — | EP | disclosed |
| EP-0438600-A1 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO COMPANY LIMITED (JP) | 1991-07-31 | — | — | EP | disclosed |
| US-4732155-A | Implantable chemoattractant system | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1988-03-22 | — | — | US | disclosed |