Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10242678 | 0.76 | — | — | |
| SCHEMBL261709 | 0.72 | — | — | |
| SCHEMBL353456 | 0.70 | — | — | |
| SCHEMBL9959966 | 0.70 | — | — | |
| SCHEMBL29184492 | 0.68 | PKM (0.49) | PKMALDH1A1RXFP1GAAHPGD | |
| Hydrochloric Acid SCHEMBL31693577 | 0.68 | PKM (0.41) | PKMALDH1A1RXFP1GAAHPGD | |
| SCHEMBL14454300 | 0.67 | PKM (0.37) | PKMALDH1A1RXFP1GAAHPGD | |
| SCHEMBL23366884 | 0.65 | PKM (0.36) | PKMALDH1A1RXFP1GAAHPGD | |
| SCHEMBL25874132 | 0.65 | PKM (0.46) | PKMALDH1A1RXFP1GAAHPGD | |
| Hydrochloric Acid SCHEMBL23354093 | 0.64 | PKM (0.36) | PKMALDH1A1RXFP1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219486-A1 | NOVEL BRIDGED BICYCLOALKYL-SUBSTITUTED AMINOTHIZOLES AND THEIR METHODS OF USE | Temple University of the Commonwealth System of Higher Education (US) | 2023-08-02 | — | — | EP | disclosed |