Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 17/20 | 1.00 |
| ▸ | PARP2 | Q9UGN5 | 16/20 | 1.00 |
| ▸ | PARP15 | Q460N3 | 16/20 | 1.00 |
| ▸ | PARP10 | Q53GL7 | 14/20 | 1.00 |
| ▸ | PARP14 | Q460N5 | 2/20 | 1.00 |
| ▸ | TNKS | O95271 | 1/20 | 1.00 |
| ▸ | PARP1 | P09874 | 1/20 | 1.00 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 1.00 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 1.00 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 1.00 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25324487 | 0.80 | PARP2 (1.00) | TNKS2PARP2PARP15PARP10PARP14 | |
| SCHEMBL25324223 | 0.76 | TNKS2 (1.00) | TNKS2PARP2PARP15PARP10PARP14 | |
| SCHEMBL25324784 | 0.76 | TNKS2 (1.00) | TNKS2PARP2PARP15PARP10PARP14 | |
| SCHEMBL2489012 | 0.75 | TNKS2 (1.00) | TNKS2PARP2PARP15PARP10PARP14 | |
| SCHEMBL11745014 | 0.73 | TNKS2 (0.72) | TNKS2PARP2PARP15PARP10PARP14 | |
| SCHEMBL11748893 | 0.72 | TNKS2 (0.66) | TNKS2PARP2PARP15PARP10PARP14 | |
| Sulfuric Acid SCHEMBL11745970 | 0.71 | TNKS2 (0.81) | TNKS2PARP2PARP15PARP10PARP14 | |
| SCHEMBL25324482 | 0.70 | TNKS2 (1.00) | TNKS2PARP2PARP15PARP10PARP14 | |
| SCHEMBL25324810 | 0.70 | PARP2 (0.67) | TNKS2PARP2PARP15PARP10PARP14 | |
| SCHEMBL18561321 | 0.69 | TNKS (0.52) | TNKS2PARP2PARP15PARP10PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144450-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | OULUN YLIOPISTO (FI) | 2023-08-03 | — | — | WO | disclosed |