Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785018 | 0.79 | SMN1; SMN2 (0.45) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL27051764 | 0.76 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL24649114 | 0.75 | SMN1; SMN2 (0.41) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL30755415 | 0.75 | ALDH1A1 (0.51) | ALDH1A1LMNAHTTSMN1; SMN2HSD17B10 | |
| SCHEMBL24785024 | 0.74 | ALDH1A1 (0.47) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL29300152 | 0.72 | ALDH1A1 (0.41) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL25702834 | 0.72 | ALDH1A1 (0.41) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL24615662 | 0.71 | HTT (0.56) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL26064294 | 0.70 | HPGD (0.44) | ALDH1A1HTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL21839495 | 0.68 | ALDH1A1 (0.51) | ALDH1A1LMNAHTTSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141300-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-07-27 | — | — | WO | disclosed |