Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | NOS3 | P29474 | 3/20 | 0.49 |
| ▸ | NOS1 | P29475 | 3/20 | 0.49 |
| ▸ | NOS2 | P35228 | 3/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25315258 | 0.98 | CYP1A2 (0.50) | CYP1A2NOS3NOS1NOS2SLC7A5 | |
| SCHEMBL2263038 | 0.83 | CYP1A2 (0.51) | CYP1A2NOS3NOS1NOS2SLC7A5 | |
| SCHEMBL5288744 | 0.82 | CYP1A2 (0.50) | CYP1A2NOS3NOS1NOS2SLC7A5 | |
| SCHEMBL7270961 | 0.82 | CYP1A2 (0.54) | CYP1A2NOS3NOS1NOS2SLC7A5 | |
| SCHEMBL31267206 | 0.82 | KDM4E (0.58) | CYP1A2NOS3NOS1NOS2SLC7A5 | |
| SCHEMBL7271800 | 0.82 | CYP1A2 (0.50) | CYP1A2NOS3NOS1NOS2SLC7A5 | |
| SCHEMBL10681044 | 0.82 | CYP1A2 (0.50) | CYP1A2NOS3NOS1NOS2SLC7A5 | |
| SCHEMBL5286221 | 0.82 | CYP1A2 (0.50) | CYP1A2NOS3NOS1NOS2SLC7A5 | |
| SCHEMBL31754264 | 0.82 | CYP1A2 (0.54) | CYP1A2NOS3NOS1NOS2SLC7A5 | |
| SCHEMBL5283008 | 0.82 | CYP1A2 (0.54) | CYP1A2NOS3NOS1NOS2SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230340018-A1 | MPRO CYSTEINE PROTEASE INHIBITORS | ANIXA BIOSCIENCES, INC. | 2023-10-26 | — | — | US | disclosed |
| US-20230234984-A1 | CYSTEINE PROTEASE INHIBITORS AND METHODS OF USE THEREOF | ANIXA BIOSCIENCES, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20230234984-A1 | CYSTEINE PROTEASE INHIBITORS AND METHODS OF USE THEREOF | ANIXA BIOSCIENCES, INC. | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234984-A1 | CYSTEINE PROTEASE INHIBITORS AND METHODS OF USE THEREOF | SERPINB1, PREP, HPN | CYP1A2 3545/4885NOS3 3946/4885NOS1 4115/4885 |
| US-20230340018-A1 | MPRO CYSTEINE PROTEASE INHIBITORS | SERPINB1, PREP, PRCP | CYP1A2 3608/4885NOS3 4567/4885NOS1 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.