Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 17/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048613 | 0.86 | NLRP3 (0.54) | NLRP3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25046903 | 0.79 | NLRP3 (0.71) | NLRP3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25048323 | 0.79 | NLRP3 (0.85) | NLRP3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL792234 | 0.78 | KCNA5 (0.48) | NLRP3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL26816569 | 0.78 | NLRP3 (0.72) | NLRP3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25048923 | 0.77 | NLRP3 (0.73) | NLRP3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25048368 | 0.77 | NLRP3 (0.87) | NLRP3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25046858 | 0.77 | NLRP3 (1.00) | NLRP3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25049531 | 0.77 | NLRP3 (0.59) | NLRP3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25048450 | 0.77 | NLRP3 (0.72) | NLRP3CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147468-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | BioAge Labs, Inc. (US) | 2023-08-03 | — | — | WO | disclosed |