Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 18/20 | 0.74 |
| ▸ | ABL1 | P00519 | 3/20 | 0.74 |
| ▸ | BCR | P11274 | 3/20 | 0.74 |
| ▸ | RAF1 | P04049 | 2/20 | 0.70 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25920375 | 0.93 | SRC (0.67) | SRCABL1BCRRAF1MAP2K1 | |
| SCHEMBL25331469 | 0.89 | SRC (0.76) | SRCABL1BCRRAF1MAP2K1 | |
| SCHEMBL6183643 | 0.88 | SRC (0.80) | SRCABL1BCR | |
| SCHEMBL25920361 | 0.87 | SRC (0.80) | SRCABL1BCRRAF1MAP2K1 | |
| SCHEMBL25331114 | 0.86 | SRC (0.68) | SRCABL1BCRRAF1MAP2K1 | |
| SCHEMBL22861713 | 0.85 | SRC (1.00) | SRCABL1BCR | |
| SCHEMBL26290127 | 0.83 | SRC (1.00) | SRCABL1BCR | |
| SCHEMBL25920241 | 0.83 | SRC (0.66) | SRCABL1BCRRAF1MAP2K1 | |
| SCHEMBL6183876 | 0.83 | SRC (0.78) | SRCABL1BCRMAP2K1 | |
| SCHEMBL25331323 | 0.83 | MAP2K1 (0.84) | SRCRAF1MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141635-A2 | HER3 LIGANDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-27 | — | — | WO | disclosed |