Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 18/20 | 0.67 |
| ▸ | ABL1 | P00519 | 5/20 | 0.65 |
| ▸ | BCR | P11274 | 5/20 | 0.65 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.61 |
| ▸ | RAF1 | P04049 | 2/20 | 0.61 |
| ▸ | STK25 | O00506 | 1/20 | 0.61 |
| ▸ | CIT | O14578 | 1/20 | 0.61 |
| ▸ | RIOK3 | O14730 | 1/20 | 0.61 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.61 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.61 |
| ▸ | CASK | O14936 | 1/20 | 0.61 |
| ▸ | GAK | O14976 | 1/20 | 0.61 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.61 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.61 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.61 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.61 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.61 |
| ▸ | JAK2 | O60674 | 1/20 | 0.61 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.61 |
| ▸ | ULK1 | O75385 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25920155 | 0.93 | SRC (0.74) | SRCABL1BCRMAP2K1RAF1 | |
| SCHEMBL25920241 | 0.91 | SRC (0.66) | SRCABL1BCRMAP2K1RAF1 | |
| SCHEMBL25920361 | 0.88 | SRC (0.80) | SRCABL1BCRMAP2K1RAF1 | |
| SCHEMBL2886333 | 0.88 | SRC (0.85) | SRCABL1BCRMAP2K1STK25 | |
| SCHEMBL29618203 | 0.88 | SRC (0.85) | SRCABL1BCRMAP2K1STK25 | |
| Hydrochloric Acid SCHEMBL19207239 | 0.87 | SRC (0.84) | SRCABL1BCRMAP2K1STK25 | |
| SCHEMBL25920307 | 0.86 | MAP2K1 (0.72) | SRCMAP2K1RAF1EGFRERBB2 | |
| SCHEMBL25920191 | 0.86 | MAP2K1 (0.84) | SRCMAP2K1RAF1EGFRERBB2 | |
| SCHEMBL6186881 | 0.84 | SRC (0.85) | SRCABL1BCRMAP2K1STK25 | |
| SCHEMBL4954921 | 0.83 | MAP2K1 (0.73) | SRCMAP2K1RAF1EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141635-A2 | HER3 LIGANDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-27 | — | — | WO | disclosed |