Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20432018 | 0.84 | CYP2C19 (0.56) | MEN1KMT2ACYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL202718 | 0.74 | MEN1 (0.61) | MEN1KMT2ACYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL20825142 | 0.73 | MEN1 (0.55) | MEN1KMT2ACYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL14355138 | 0.72 | MEN1 (0.59) | MEN1KMT2ACYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL196487 | 0.72 | KMT2A (0.70) | MEN1KMT2ACYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL20860932 | 0.71 | LMNA (0.41) | MEN1KMT2AALDH1A1HPGDRAB9A | |
| SCHEMBL9921513 | 0.70 | MEN1 (0.41) | MEN1KMT2ACYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL18833760 | 0.70 | MEN1 (0.51) | MEN1KMT2ACYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL24242175 | 0.69 | MEN1 (0.50) | MEN1KMT2ACYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL10157129 | 0.69 | MEN1 (0.59) | MEN1KMT2ACYP2C19CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219501-A1 | COMPOUND CONTAINING 2,4-THIAZOLE RING, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Shandong University (CN) | 2023-08-02 | — | — | EP | disclosed |