SCHEMBL25922136

SCHEMBL25922136

CCOP(=O)(OCC)C(Cc1ccc(C)cc1)P(=O)(OCC)OCC

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 3/20 0.56
MAPT P10636 1/20 0.44
POLB P06746 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
NPSR1 Q6W5P4 1/20 0.39
KDM4E B2RXH2 1/20 0.38
EPHX2 P34913 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
GAA P10253 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25922141 0.84 HMGCR (0.56) HMGCRMAPTPOLBNPSR1EPHX2
SCHEMBL5003858 0.84 HMGCR (0.51) HMGCRMAPTPOLBKDM4EGAA
SCHEMBL5664710 0.84 HMGCR (0.57) HMGCRPOLBEPHX2GAA
SCHEMBL8589065 0.81 HMGCR (0.49) HMGCRCA12CA1CA2CA9
SCHEMBL8170507 0.81 HMGCR (0.55) HMGCRMAPTPOLBKDM4EEPHX2
SCHEMBL12440416 0.80 HMGCR (0.38) HMGCRKDM4EGAAALDH1A1
SCHEMBL5007391 0.79 CA1 (0.54) HMGCRMAPTCA1CA2NPSR1
SCHEMBL8673055 0.79 HMGCR (0.43) HMGCRMAPTCA12CA1CA2
SCHEMBL2807785 0.78 HMGCR (0.48) HMGCRMAPTPOLBKDM4EGAA
SCHEMBL12876205 0.76 POLB (0.50) HMGCRMAPTPOLBNPSR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242689-A1 POLYMER, COPOLYMER, INK, INK CONTAINER, IMAGE FORMING METHOD, IMAGE FORMING DEVICE, AND BACKSHEET FOR SOLAR CELL RICOH COMPANY, LTD. (JP) 2023-08-03 US disclosed