Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | IL6ST | P40189 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 7/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25923151 | 1.00 | PPARA (0.47) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL22552990 | 0.87 | PPARA (0.59) | PPARAIL6STNAAAIDH1PPARG | |
| SCHEMBL20825575 | 0.87 | PPARA (0.59) | PPARAIL6STNAAAIDH1PPARG | |
| SCHEMBL20820036 | 0.87 | PPARA (0.59) | PPARAIL6STNAAAIDH1PPARG | |
| SCHEMBL28900400 | 0.87 | PPARA (0.59) | PPARAIL6STNAAAIDH1PPARG | |
| SCHEMBL28900402 | 0.87 | PPARA (0.59) | PPARAIL6STNAAAIDH1PPARG | |
| SCHEMBL22552723 | 0.87 | PPARA (0.59) | PPARAIL6STNAAAIDH1PPARG | |
| SCHEMBL13295722 | 0.86 | PPARA (0.58) | PPARAIL6STNAAAIDH1PPARG | |
| SCHEMBL28582205 | 0.86 | PPARA (0.58) | PPARAIL6STNAAAIDH1PPARG | |
| SCHEMBL3495345 | 0.86 | PPARA (0.51) | PPARAIL6STNAAAIDH1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242482-A9 | DISCOVERY, TOTAL SYNTHESIS, AND BIOACTIVITY OF DOSCADENAMIDES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-08-03 | — | — | US | disclosed |
| US-20230242482-A9 | DISCOVERY, TOTAL SYNTHESIS, AND BIOACTIVITY OF DOSCADENAMIDES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242482-A9 | DISCOVERY, TOTAL SYNTHESIS, AND BIOACTIVITY OF DOSCADENAMIDES | PDE9A, CGAS, PDE8A | PPARA 3388/4885IL6ST 3777/4885NAAA 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.