Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | IL6ST | P40189 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 7/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3493546 | 0.99 | PPARA (0.51) | PPARAIL6STNAAAFAAHIDH1 | |
| SCHEMBL28950479 | 0.99 | PPARA (0.51) | PPARAIL6STNAAAFAAHIDH1 | |
| SCHEMBL28950477 | 0.99 | PPARA (0.51) | PPARAIL6STNAAAFAAHIDH1 | |
| SCHEMBL23970492 | 0.99 | PPARA (0.51) | PPARAIL6STNAAAFAAHIDH1 | |
| SCHEMBL357656 | 0.97 | PPARA (0.50) | PPARAIL6STNAAAFAAHIDH1 | |
| SCHEMBL357655 | 0.97 | PPARA (0.50) | PPARAIL6STNAAAFAAHIDH1 | |
| SCHEMBL22552990 | 0.90 | PPARA (0.59) | PPARAIL6STNAAAIDH1ABCB1 | |
| SCHEMBL20825575 | 0.90 | PPARA (0.59) | PPARAIL6STNAAAIDH1ABCB1 | |
| SCHEMBL20820036 | 0.90 | PPARA (0.59) | PPARAIL6STNAAAIDH1ABCB1 | |
| SCHEMBL22552723 | 0.90 | PPARA (0.59) | PPARAIL6STNAAAIDH1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359291-B2 | Non-natural amino acids | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2016-06-07 | — | — | US | disclosed |
| US-20130217632-A1 | Non-Natural Amino Acids | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2013-08-22 | — | — | US | disclosed |
| US-20100130432-A1 | Non-Natural Amino Acids and Neurotensin Analogues Thereof | Argolyn Bioscience Inc. and Medical University of South Carolina [MUSC] | 2010-05-27 | — | — | US | disclosed |
| EP-1962884-A2 | NON-NATURAL AMINO ACIDS AND NEUROTENSIN ANALOGUES THEREOF | Argolyn Bioscience, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| US-20080139481-A1 | Non-Natural Amino Acids | DIX THOMAS A | 2008-06-12 | — | — | US | disclosed |
| WO-2007070672-A2 | NON-NATURAL AMINO ACIDS AND NEUROTENSIN ANALOGUES THEREOF | ARGOLYN BIOSCIENCE, INC. (US) | 2007-06-21 | — | — | WO | disclosed |
| EP-1768951-A2 | NON-NATURAL AMINO ACIDS | MUSC Foundation For Research Development (US) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006009902-A2 | NON-NATURAL AMINO ACIDS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217632-A1 | Non-Natural Amino Acids | NGLY1, NPPA, DNPEP | PPARA 4527/4885IL6ST 3722/4885NAAA 51/4885 |
| US-20080139481-A1 | Non-Natural Amino Acids | NGLY1, DNPEP, NTSR1 | PPARA 4570/4885IL6ST 3532/4885NAAA 42/4885 |
| US-20100130432-A1 | Non-Natural Amino Acids and Neurotensin Analogues Thereof | NGLY1, NTSR1, NTSR2 | PPARA 4554/4885IL6ST 2948/4885NAAA 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.