Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023882 | 0.84 | POLB (0.64) | POLBCASP6PLA2G4BALDH1A1HPGD | |
| SCHEMBL7336764 | 0.81 | ALDH1A1 (0.67) | POLBCASP6PLA2G4BALDH1A1HPGD | |
| SCHEMBL991684 | 0.80 | POLB (0.48) | THRATHRBPOLBCASP6ALDH1A1 | |
| SCHEMBL9512861 | 0.80 | ALDH1A1 (0.65) | POLBCASP6PLA2G4BALDH1A1HPGD | |
| SCHEMBL1199847 | 0.80 | ALDH1A1 (0.69) | POLBCASP6PLA2G4BALDH1A1HPGD | |
| SCHEMBL1201602 | 0.80 | ALDH1A1 (0.69) | POLBCASP6PLA2G4BALDH1A1HPGD | |
| SCHEMBL1199953 | 0.80 | ALDH1A1 (0.69) | POLBCASP6PLA2G4BALDH1A1HPGD | |
| SCHEMBL1200986 | 0.80 | ALDH1A1 (0.69) | POLBCASP6PLA2G4BALDH1A1HPGD | |
| SCHEMBL1199892 | 0.80 | ALDH1A1 (0.69) | POLBCASP6PLA2G4BALDH1A1HPGD | |
| SCHEMBL1231278 | 0.80 | ALDH1A1 (0.69) | POLBCASP6PLA2G4BALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011140009-A1 | METHODS OF USING SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | BIOMARIN PHARMACEUTICAL INC. (US) | 2011-11-10 | — | — | WO | disclosed |