Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.43 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.43 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.43 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18226799 | 0.88 | DPP4 (0.51) | HPGDDPP4RECQLEPHX1GPR119 | |
| SCHEMBL7273992 | 0.87 | HPGD (0.48) | HPGDDPP4RECQLEPHX1GPR119 | |
| SCHEMBL25343622 | 0.84 | HPGD (0.54) | HPGDDPP4RECQLEPHX1GPR119 | |
| SCHEMBL1892198 | 0.83 | HPGD (0.53) | HPGDDPP4RECQLEPHX1GPR119 | |
| SCHEMBL5341723 | 0.81 | HPGD (0.54) | HPGDDPP4RECQLEPHX1GPR119 | |
| SCHEMBL5946873 | 0.80 | HPGD (0.50) | HPGDDPP4RECQLEPHX1GPR119 | |
| SCHEMBL25522993 | 0.80 | HPGD (0.50) | HPGDDPP4RECQLEPHX1GPR119 | |
| SCHEMBL16225010 | 0.80 | DPP4 (0.42) | HPGDDPP4RECQLEPHX1GPR119 | |
| SCHEMBL19457339 | 0.80 | HPGD (0.53) | HPGDDPP4RECQLEPHX1GPR119 | |
| SCHEMBL5947150 | 0.79 | HPGD (0.47) | HPGDDPP4RECQLEPHX1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023142754-A1 | EZH1/2 INHIBITOR, PREPARATION THEREOF, AND USE THEREOF IN ANTI-TUMOR THERAPY | 江苏天士力帝益药业有限公司 | 2023-08-03 | — | — | WO | disclosed |