⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726089 | 0.87 | MAPT (0.33) | — | |
| SCHEMBL1569387 | 0.77 | — | — | |
| SCHEMBL11347878 | 0.77 | — | — | |
| SCHEMBL4572759 | 0.77 | — | — | |
| SCHEMBL30940213 | 0.77 | — | — | |
| SCHEMBL2592792 | 0.75 | MAPT (0.36) | — | |
| SCHEMBL17783706 | 0.75 | MAPT (0.33) | — | |
| SCHEMBL11606692 | 0.75 | ALDH1A1 (0.45) | — | |
| SCHEMBL23094091 | 0.73 | MAPT (0.33) | — | |
| SCHEMBL16202726 | 0.73 | MAPT (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874745-A | Thiophene derivative conjugated polymer containing amphoteric ions and preparation method and application thereof | 浙江工业大学 | 2023-10-13 | — | — | CN | disclosed |
| US-20230235388-A1 | COMPOSITIONS AND METHODS FOR SEQUENCING USING AT LEAST ALTERING ELECTRICAL CHARACTERISTICS OF BRIDGES BETWEEN ELECTRODES | ILLUMINA SINGAPORE PTE. LTD. (SG) | 2023-07-27 | — | — | US | disclosed |
| US-20230235388-A1 | COMPOSITIONS AND METHODS FOR SEQUENCING USING AT LEAST ALTERING ELECTRICAL CHARACTERISTICS OF BRIDGES BETWEEN ELECTRODES | ILLUMINA SINGAPORE PTE. LTD. (SG) | 2023-07-27 | — | — | US | disclosed |
| WO-2022005395-A1 | COMPOSITIONS AND METHODS FOR SEQUENCING USING AT LEAST ALTERING ELECTRICAL CHARACTERISTICS OF BRIDGES BETWEEN ELECTRODES | ILLUMINA SINGAPORE PTE. LTD. (SG) | 2022-01-06 | — | — | WO | disclosed |
| WO-2020250223-A1 | NOVEL NON-CODING HETEROCYCLIC AMINO ACIDS (NCHAA) AND THEIR USE AS HERBICIDES | FORTEPHEST LTD. (IL) | 2020-12-17 | — | — | WO | disclosed |
| US-9567321-B2 | Aromatic monomers deriving from glycerol units, process for their preparation and use thereof for the preparation of water-soluble conjugated polymers | ENI S.P.A. (IT) | 2017-02-14 | — | — | US | disclosed |
| US-9567321-B2 | Aromatic monomers deriving from glycerol units, process for their preparation and use thereof for the preparation of water-soluble conjugated polymers | ENI S.P.A. (IT) | 2017-02-14 | — | — | US | disclosed |
| US-9567321-B2 | Aromatic monomers deriving from glycerol units, process for their preparation and use thereof for the preparation of water-soluble conjugated polymers | ENI S.P.A. (IT) | 2017-02-14 | — | — | US | disclosed |
| US-9416139-B2 | Spiro ring compound as hepatitis C virus (HCV) inhibitor and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-08-16 | — | — | US | disclosed |
| US-9416139-B2 | Spiro ring compound as hepatitis C virus (HCV) inhibitor and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-08-16 | — | — | US | disclosed |
| EP-1135682-A4 | NANOPARTICLES WITH POLYMER SHELLS | NANOSPHERE INC (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1135682-A1 | NANOPARTICLES WITH POLYMER SHELLS | Nanosphere, Inc. (US) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000033079-A1 | NANOPARTICLES WITH POLYMER SHELLS | NANOSPHERE, INC. (US) | 2000-06-08 | — | — | WO | disclosed |
| WO-1998000430-A1 | IMIDAZOL DERIVATIVES USEFUL AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-08 | — | — | WO | disclosed |
| EP-0382106-B1 | Process for manufacturing thiophene derivatives | HOECHST AG (DE) | 1995-06-07 | — | — | EP | disclosed |
| US-5118813-A | PROCESS FOR THE PREPARATION OF COMPOUNDS WITH ANTIULCER ACTION | BIOTE KFARMA SRL (IT) | 1992-06-02 | — | — | US | disclosed |
| US-5100520-A | Electrochemical Dehalogenation | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| EP-0382106-A2 | Process for manufacturing thiophene derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-16 | — | — | EP | disclosed |
| US-4639436-A | Antidiabetic 3,4,5-trihydroxypiperidines | BAYER AKTIENGESELLSCHAFT (DE) | 1987-01-27 | — | — | US | disclosed |
| US-4260622-A | Animal feedstuffs employing 3,4,5-trihydroxypiperidines | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |