SCHEMBL25924978

SCHEMBL25924978

CC(Cl)OCOC(=O)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.40
BTN3A1 O00481 5/20 0.34
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ENO1 P06733 1/20 0.31
MMP8 P22894 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13020675 0.83 PRKCA (0.42) PRKCABTN3A1ALDH1A1POLBGAA
SCHEMBL13531163 0.78 PRKCA (0.39) PRKCABTN3A1ALDH1A1POLBGAA
SCHEMBL681950 0.77 PRKCA (0.46) PRKCABTN3A1ALDH1A1POLBGAA
SCHEMBL13349186 0.75 PRKCA (0.44) PRKCABTN3A1ALDH1A1POLBGAA
SCHEMBL10253729 0.74 PRKCA (0.42) PRKCABTN3A1ALDH1A1POLBGAA
SCHEMBL27999368 0.72 PRKCA (0.43) PRKCABTN3A1ALDH1A1POLBGAA
SCHEMBL5534787 0.72 PRKCA (0.43) PRKCABTN3A1ALDH1A1POLBGAA
SCHEMBL390512 0.71 PRKCA (0.39) PRKCABTN3A1ALDH1A1POLBGAA
SCHEMBL6840505 0.71 PRKCA (0.40) PRKCABTN3A1ALDH1A1POLBGAA
SCHEMBL19235874 0.71 PRKCA (0.40) PRKCABTN3A1ALDH1A1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230233593-A1 ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS VenatoRx Pharmaceuticals, Inc. 2023-07-27 US disclosed
US-11638715-B2 Orally-bioavailable nucleoside analogs VenatoRx Pharmaceuticals, Inc. (US) 2023-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11638715-B2 Orally-bioavailable nucleoside analogs SLC29A2, SLC29A1, PNP PRKCA 3887/4885BTN3A1 4836/4885ALDH1A1 2219/4885
US-20230233593-A1 ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS SLC29A2, SLC29A1, PNP PRKCA 3887/4885BTN3A1 4836/4885ALDH1A1 2219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.