Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 12/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 4/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22169791 | 0.90 | MEN1 (0.42) | MEN1KMT2AMTNR1AMTNR1BABCB11 | |
| SCHEMBL5383679 | 0.87 | MEN1 (0.54) | MEN1KMT2AMTNR1AMTNR1BABCB11 | |
| SCHEMBL13070014 | 0.84 | ALDH1A1 (0.42) | ALDH1A1NAMPTPRMT3EPHX1 | |
| SCHEMBL15759098 | 0.83 | ALDH1A1 (0.47) | MEN1KMT2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL931401 | 0.81 | EPHX1 (0.56) | MEN1KMT2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL9893063 | 0.81 | BRD4 (0.43) | MTNR1AMTNR1BALDH1A1NQO2NAMPT | |
| SCHEMBL9893127 | 0.81 | EPHX1 (0.56) | MEN1KMT2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL14321920 | 0.81 | NPC1 (0.42) | MEN1KMT2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL15248911 | 0.80 | NAMPT (0.40) | ALDH1A1NAMPTPRMT3POLBEPHX1 | |
| SCHEMBL6119947 | 0.79 | NAMPT (0.41) | ALDH1A1NAMPTPRMT3EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219502-A1 | IMIDAZO[1,5-A]PYRAZINE DERIVATIVES AS PI3KDELTA INHIBITORS | BeiGene, Ltd. (KY) | 2023-08-02 | — | — | EP | disclosed |