SCHEMBL25925604 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	BRD9	Q9H8M2	15/20	0.65

▸	BRD4	O60885	14/20	0.65

▸	BRD7	Q9NPI1	10/20	0.65

▸	BRD2	P25440	4/20	0.65

▸	ERN1	O75460	1/20	0.40

▸	TAF1	P21675	1/20	0.39

▸	TGFBR1	P36897	1/20	0.39

▸	BRPF1	P55201	1/20	0.39

▸	ACVR1	Q04771	1/20	0.39

▸	BPTF	Q12830	1/20	0.39

▸	TAF1L	Q8IZX4	1/20	0.39

▸	CREBBP	Q92793	1/20	0.39

▸	CECR2	Q9BXF3	1/20	0.39

▸	BAZ2B	Q9UIF8	1/20	0.39

▸	ATAD2B	Q9ULI0	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23134701	0.89	BRD4 (0.70)	BRD9BRD4BRD7BRD2ERN1
SCHEMBL25925462	0.84	BRD4 (0.48)	BRD9BRD4BRD7BRD2ERN1
SCHEMBL25925473	0.84	BRD4 (0.48)	BRD9BRD4BRD7BRD2ERN1
SCHEMBL25925475	0.83	BRD9 (0.47)	BRD9BRD4BRD7BRD2ERN1
SCHEMBL25925479	0.83	BRD9 (0.47)	BRD9BRD4BRD7BRD2ERN1
SCHEMBL25925521	0.82	BRD4 (0.62)	BRD9BRD4BRD7BRD2ERN1
SCHEMBL23123760	0.82	BRD4 (0.62)	BRD9BRD4BRD7BRD2ERN1
SCHEMBL23134735	0.81	BRD4 (0.61)	BRD9BRD4BRD7BRD2ERN1
SCHEMBL23783319	0.81	BRD4 (0.61)	BRD9BRD4BRD7BRD2ERN1
SCHEMBL19869768	0.81	BRD9 (0.72)	BRD9BRD4BRD7BRD2ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023109892-A1	COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF	海思科医药集团股份有限公司	2023-06-22	—	—	WO	disclosed