Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 13/20 | 0.47 |
| ▸ | BRD4 | O60885 | 13/20 | 0.47 |
| ▸ | BRD7 | Q9NPI1 | 9/20 | 0.47 |
| ▸ | BRD2 | P25440 | 4/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.37 |
| ▸ | TAF1 | P21675 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | ATAD2B | Q9ULI0 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25925479 | 0.90 | BRD9 (0.47) | BRD9BRD4BRD7BRD2TGFBR1 | |
| SCHEMBL25925604 | 0.83 | BRD9 (0.65) | BRD9BRD4BRD7BRD2TGFBR1 | |
| SCHEMBL25929854 | 0.77 | BRD9 (0.44) | BRD9BRD4BRD7BRD2TGFBR1 | |
| SCHEMBL25925462 | 0.73 | BRD4 (0.48) | BRD9BRD4BRD7BRD2TGFBR1 | |
| SCHEMBL25925473 | 0.73 | BRD4 (0.48) | BRD9BRD4BRD7BRD2TGFBR1 | |
| SCHEMBL25925481 | 0.73 | BRD9 (0.41) | BRD9BRD4BRD7BRD2TGFBR1 | |
| SCHEMBL23134701 | 0.72 | BRD4 (0.70) | BRD9BRD4BRD7BRD2TGFBR1 | |
| SCHEMBL25925483 | 0.71 | BRD9 (0.45) | BRD9BRD4BRD7BRD2TGFBR1 | |
| SCHEMBL23123760 | 0.67 | BRD4 (0.62) | BRD9BRD4BRD7BRD2TGFBR1 | |
| SCHEMBL25925521 | 0.67 | BRD4 (0.62) | BRD9BRD4BRD7BRD2TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109892-A1 | COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |