SCHEMBL25925820

SCHEMBL25925820

CC(=O)c1ccc(C(=O)OCCOC(=O)c2ccc(C(=O)OCCOC(=O)c3ccc(C(=O)OCCO)cc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.50
TSHR P16473 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CHRM1 P11229 1/20 0.50
SLC6A2 P23975 1/20 0.50
KDR P35968 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.48
LMNA P02545 3/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 2/20 0.47
MAPK1 P28482 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CYP2D6 P10635 1/20 0.47
NR1H2 P55055 1/20 0.47
RNASEL Q05823 1/20 0.47
GAA P10253 1/20 0.47
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
PDE4D Q08499 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1645843 0.98 TSHR (0.52) ESR1TSHRTDP1ALDH1A1CHRM1
SCHEMBL15395914 0.92 ESR1 (0.57) ESR1TSHRTDP1ALDH1A1CHRM1
Acetone SCHEMBL28904622 0.90 TSHR (0.55) ESR1TSHRTDP1ALDH1A1CHRM1
SCHEMBL19235060 0.90 TDP1 (0.54) ESR1TSHRTDP1ALDH1A1CHRM1
SCHEMBL26453328 0.90 TDP1 (0.54) ESR1TSHRTDP1ALDH1A1CHRM1
SCHEMBL13292517 0.90 TDP1 (0.54) ESR1TSHRTDP1ALDH1A1CHRM1
SCHEMBL12442300 0.89 ESR1 (0.50) ESR1TSHRTDP1ALDH1A1CHRM1
SCHEMBL26378 0.88 TDP1 (0.56) ESR1TSHRTDP1ALDH1A1CHRM1
SCHEMBL23928039 0.86 ESR1 (0.52) ESR1TSHRTDP1ALDH1A1CHRM1
SCHEMBL23928020 0.86 ESR1 (0.52) ESR1TSHRTDP1ALDH1A1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250228-A1 POLYESTER RESIN AND METHOD FOR PRODUCING BLOW-MOLDED PRODUCT MADE OF POLYESTER RESIN TOYOBO CO., LTD. (JP) 2023-08-10 US disclosed