SCHEMBL26378

SCHEMBL26378

O=C(OCCO)c1ccc(C(=O)OCCO)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.56
ESR1 P03372 4/20 0.55
TSHR P16473 4/20 0.55
ALDH1A1 P00352 3/20 0.55
CHRM1 P11229 1/20 0.55
SLC6A2 P23975 1/20 0.55
KDR P35968 1/20 0.55
LMNA P02545 4/20 0.52
CYP1A2 P05177 3/20 0.52
CYP2C19 P33261 2/20 0.52
CYP2D6 P10635 2/20 0.52
MAPK1 P28482 1/20 0.52
NR1H2 P55055 1/20 0.52
RNASEL Q05823 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CYP3A4 P08684 2/20 0.50
CYP2C9 P11712 1/20 0.50
PDE4D Q08499 1/20 0.50
ESR2 Q92731 2/20 0.48
PHLPP2 Q6ZVD8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26453328 0.98 TDP1 (0.54) TDP1ESR1TSHRALDH1A1CHRM1
Ethylene Glycol SCHEMBL28198373 0.98 TDP1 (0.54) TDP1ESR1TSHRALDH1A1CHRM1
Lithium SCHEMBL30805733 0.98 TDP1 (0.54) TDP1ESR1TSHRALDH1A1CHRM1
SCHEMBL19235060 0.98 TDP1 (0.54) TDP1ESR1TSHRALDH1A1CHRM1
SCHEMBL13292517 0.98 TDP1 (0.54) TDP1ESR1TSHRALDH1A1CHRM1
Ethylene SCHEMBL29751612 0.95 TDP1 (0.52) TDP1ESR1TSHRALDH1A1CHRM1
SCHEMBL12446498 0.93 ESR1 (0.50) TDP1ESR1TSHRALDH1A1CHRM1
SCHEMBL8828042 0.93 LMNA (0.50) TDP1ESR1TSHRALDH1A1CHRM1
Acetone SCHEMBL28904622 0.93 TSHR (0.55) TDP1ESR1TSHRALDH1A1CHRM1
1,4-Butanediol SCHEMBL7108461 0.93 TDP1 (0.55) TDP1ESR1TSHRALDH1A1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 24681 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4357389-B1 POLYESTER RESIN COMPRISING REGENERATED BIS(2-HYDROXYETHYL)TEREPHTHALATE AND FILM SK CHEMICALS CO LTD (KR) 2026-05-27 EP claimed
CN-122094929-A Regenerated raw material composition and preparation method thereof 2026-05-26 CN claimed
WO-2026104237-A1 METHOD FOR RECYCLING POLYETHYLENE TEREPHTHALATE BY GLYCOLYSIS, COMPRISING A STEP OF SEPARATING OTHER POLYMERS IFP Energies Nouvelles (FR) 2026-05-21 WO claimed
US-20260139117-A1 MECHANOCATALYTIC DEPOLYMERIZATION OF PLASTICS GEORGIA TECH RES CORPORATION (US) 2026-05-21 US claimed
CN-122055404-A Polyester heat-shrinkable film with improved shrink properties SK化学公司 2026-05-15 CN claimed
CN-122037117-A Cationic polyurethane polysiloxane copolymer and polyester fabric washable soft finishing agent containing same 杭州传化精细化工有限公司 2026-05-15 CN claimed
CN-122055352-A Method for purifying terephthalic acid esters by adsorption and adsorbent regeneration IFP 新能源公司 2026-05-15 CN claimed
CN-122011374-A Method for preparing high-heat-resistance high-transparency polyester amide by recycling waste PET 浙江恒逸石化研究院有限公司 2026-05-12 CN claimed
US-12624188-B2 Method for producing bis-2-hydroxyethyl terephthalate through continuous depolymerization SK CHEMICALS CO., LTD. (KR) 2026-05-12 US claimed
CN-122011347-A Regeneration preparation method of PETG or PCTG copolyester 中国石油化工股份有限公司 2026-05-12 CN claimed
US-4001187-A CONTINUOUS PROCESSING KANEBO, LTD. (JA) 1977-01-04 US claimed
US-3991035-A TREATING WITH HYPOCHLOROUS ACID; PILLING RESISTANCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-11-09 US claimed
US-3986828-A POLYMER FABRIC COMPACTING PROCESS MEADOX MEDICALS, INC. (US) 1976-10-19 US claimed
US-3972852-A Process for preparing aromatic polyesters from diphenols TEIJIN LIMITED (JA) 1976-08-03 US claimed
US-3962299-A Organopolysiloxane polyesters CELANESE CORPORATION (US) 1976-06-08 US claimed
US-3960806-A Flame resistant linear polyesters EMERY INDUSTRIES, INC. (US) 1976-06-01 US claimed
US-3958177-A PARTICLE ANALYZING DEVICE WITH CHANGEABLE APERTURE MEANS SHERWOOD MEDICAL INDUSTRIES INC. (US) 1976-05-18 US claimed
US-3954841-A Curable resin compositions CELANESE CORPORATION (US) 1976-05-04 US claimed
US-3954901-A HEXAKIS(ALKOXYMETHYL)MELAMINE HARDENER NIPPON ESTER CO., LTD. (JA) 1976-05-04 US claimed
US-3936404-A Aqueous baking varnishes from carboxylic polyester and carboxylic polyimide, and coated article NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) 1976-02-03 US claimed