SCHEMBL25925850

SCHEMBL25925850

Cc1c(O)c(/N=N/c2ncnc(Cl)c2Cl)cc(/N=N/c2snc3cccnc23)c1O

nearest known ligand 0.31

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.31
MAPT P10636 2/20 0.31
HTT P42858 2/20 0.31
KMT2A Q03164 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
AGTR1 P30556 1/20 0.31
HKDC1 Q2TB90 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
KCNH2 Q12809 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25925859 0.85
SCHEMBL25925841 0.79 MEN1 (0.34) MEN1MAPTHTTKMT2ATDP1
SCHEMBL25925849 0.78 MAPT (0.34) MEN1MAPTHTTKMT2ATDP1
SCHEMBL25925847 0.77 MEN1 (0.32) MEN1MAPTHTTKMT2ATDP1
SCHEMBL25925839 0.76
SCHEMBL25927695 0.75 MEN1 (0.32) MEN1MAPTHTTKMT2ATDP1
SCHEMBL25925843 0.75 MEN1 (0.31) MEN1MAPTHTTKMT2ATDP1
SCHEMBL25927687 0.74 MEN1 (0.31) MEN1MAPTHTTKMT2ATDP1
SCHEMBL25927794 0.74 GLO1 (0.32)
SCHEMBL25925858 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE FUJIFILM CORPORATION (JP) 2023-08-03 US disclosed
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE FUJIFILM CORPORATION (JP) 2023-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE AR, MAPT, NR5A1 MEN1 67/4885MAPT 2/4885HTT 136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.