SCHEMBL25925876

SCHEMBL25925876

COc1cc(/N=N/c2nc(SC)ns2)c(O)c(/N=N/c2ccnn2C)c1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.33
RAB9A P51151 3/20 0.33
NPC1 O15118 2/20 0.33
MEN1 O00255 2/20 0.33
POLB P06746 2/20 0.32
HSP90AA1 P07900 1/20 0.30
OPRK1 P41145 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25925730 0.86
SCHEMBL25925868 0.85 HSP90AA1 (0.31) HSP90AA1
SCHEMBL25925883 0.84
SCHEMBL25925873 0.83 RAB9A (0.36) KMT2ARAB9ANPC1MEN1POLB
SCHEMBL25925706 0.82
SCHEMBL25925732 0.81
SCHEMBL25925952 0.79
SCHEMBL25925927 0.76 KMT2A (0.43) KMT2ARAB9ANPC1MEN1POLB
SCHEMBL25925880 0.75 MAPT (0.33) KMT2ARAB9ANPC1MEN1POLB
SCHEMBL25925924 0.71 RAB9A (0.46) KMT2ARAB9ANPC1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE FUJIFILM CORPORATION (JP) 2023-08-03 US disclosed
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE FUJIFILM CORPORATION (JP) 2023-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE AR, MAPT, NR5A1 KMT2A 1814/4885RAB9A 1490/4885NPC1 962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.