Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2592598 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TAAR1SMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL12176875 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TAAR1SMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL14717751 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TAAR1SMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL28543277 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TAAR1SMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL28542547 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TAAR1SMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL2588683 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TAAR1SMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL28543278 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TAAR1SMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL2591701 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TAAR1SMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL2588680 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TAAR1SMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL11267310 | 0.73 | TDP1 (0.49) | ALDH1A1TAAR1SMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2899185-B1 | Processes for preparing linezolid | UNIV INDIANA RES & TECH CORP (US) | 2018-01-31 | — | — | EP | disclosed |
| EP-2563781-B1 | PROCESSES FOR PREPARING LINEZOLID | UNIV INDIANA RES & TECH CORP (US) | 2016-10-26 | — | — | EP | disclosed |
| US-20160024032-A1 | PROCESSES FOR PREPARING LINEZOLID | UNIV INDIANA RES & TECH CORP (US) | 2016-01-28 | — | — | US | disclosed |
| EP-2899185-A1 | Processes for preparing linezolid | Indiana University Research and Technology Corporation (US) | 2015-07-29 | — | — | EP | disclosed |
| EP-2563781-A1 | PROCESSES FOR PREPARING LINEZOLID | Indiana University Research and Technology Corporation (US) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011137222-A1 | PROCESSES FOR PREPARING LINEZOLID | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2011-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024032-A1 | PROCESSES FOR PREPARING LINEZOLID | CYP2C9, CYP2C19, CYP3A43 | ALDH1A1 703/4885TAAR1 4586/4885SMN1; SMN2 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.