SCHEMBL25925935

SCHEMBL25925935

Cn1nccc1/N=N/c1c(O)c(O)cc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPL P40238 4/20 0.48
MEN1 O00255 7/20 0.39
KMT2A Q03164 7/20 0.39
MITF O75030 1/20 0.39
MAPT P10636 8/20 0.38
L3MBTL1 Q9Y468 6/20 0.38
TDP1 Q9NUW8 5/20 0.38
NPC1 O15118 4/20 0.38
POLB P06746 4/20 0.38
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 4/20 0.38
HSP90AA1 P07900 3/20 0.38
LMNA P02545 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
HPGD P15428 1/20 0.38
ALOX12 P18054 1/20 0.38
OPRK1 P41145 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
RECQL P46063 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25925899 0.84 MAPT (0.35) MPLMEN1KMT2AMITFMAPT
SCHEMBL10265903 0.83 MEN1 (0.47) MPLMEN1KMT2AMITFMAPT
SCHEMBL25925733 0.77 ALDH1A1 (0.36) MAPTALDH1A1
SCHEMBL25925936 0.77
SCHEMBL25925937 0.77
SCHEMBL25925901 0.76 MGAM (0.33) MEN1KMT2AMAPTL3MBTL1TDP1
SCHEMBL25925932 0.74 ESR1 (0.33) MEN1KMT2AMAPTTDP1ALDH1A1
SCHEMBL25925882 0.71 AHR (0.36) MEN1KMT2AMAPTL3MBTL1TDP1
SCHEMBL25925704 0.71 MAPT (0.33) MEN1KMT2AMAPTL3MBTL1TDP1
SCHEMBL25925862 0.70 MAPT (0.34) MEN1KMT2AMAPTL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE FUJIFILM CORPORATION (JP) 2023-08-03 US disclosed
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE FUJIFILM CORPORATION (JP) 2023-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242523-A1 COMPOUND, TAUTOMER OF COMPOUND OR SALT OF COMPOUND OR TAUTOMER, METHOD FOR PRODUCING SAME, COLORING COMPOSITION, DYEING METHOD, AND DYED ARTICLE AR, MAPT, NR5A1 MPL 3953/4885MEN1 67/4885KMT2A 1814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.