Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10778251 | 0.77 | CYP3A4 (0.41) | CYP3A4MAPK1CYP2A6AHR | |
| SCHEMBL30435783 | 0.72 | CYP3A4 (0.38) | CYP3A4MAPK1CYP2A6AHR | |
| SCHEMBL4357969 | 0.72 | CYP3A4 (0.38) | CYP3A4MAPK1CYP2A6AHR | |
| SCHEMBL30354095 | 0.72 | CYP3A4 (0.38) | CYP3A4MAPK1CYP2A6AHR | |
| SCHEMBL2159908 | 0.66 | IDO1 (0.39) | CYP3A4MAPK1CYP2A6AHR | |
| SCHEMBL28685336 | 0.66 | IDO1 (0.39) | CYP3A4MAPK1CYP2A6AHR | |
| SCHEMBL29368277 | 0.65 | CYP3A4 (0.62) | CYP3A4MAPK1CYP2A6AHR | |
| SCHEMBL348089 | 0.65 | CYP3A4 (0.62) | CYP3A4MAPK1CYP2A6AHR | |
| SCHEMBL16291614 | 0.64 | CYP2A6 (0.37) | CYP3A4MAPK1CYP2A6AHR | |
| SCHEMBL1950280 | 0.63 | CYP3A4 (0.46) | CYP3A4MAPK1CYP2A6AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242551-A1 | ISOTOPE-SUBSTITUTED SPIRO AROMATIC RING COMPOUND AND APPLICATION THEREOF | ETERN BIOPHARMA (SHANGHAI) CO., LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242551-A1 | ISOTOPE-SUBSTITUTED SPIRO AROMATIC RING COMPOUND AND APPLICATION THEREOF | SLCO1B1, SLCO1B3, SLCO2B1 | CYP3A4 35/4885MAPK1 2159/4885CYP2A6 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.