SCHEMBL4357969

SCHEMBL4357969

Sc1ccc(Cl)c(Cl)c1S.Sc1ccc(Cl)c(Cl)c1S.[Ni]

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
CYP2A6 P11509 2/20 0.33
AHR P35869 2/20 0.32
TDP1 Q9NUW8 1/20 0.31
TSHR P16473 1/20 0.31
CYP1A2 P05177 1/20 0.30
IDO1 P14902 1/20 0.30
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30435783 1.00 CYP3A4 (0.38) CYP3A4MAPK1CYP2A6AHRTDP1
SCHEMBL30354095 1.00 CYP3A4 (0.38) CYP3A4MAPK1CYP2A6AHRTDP1
SCHEMBL10778251 0.81 CYP3A4 (0.41) CYP3A4MAPK1CYP2A6AHRTDP1
SCHEMBL1950280 0.79 CYP3A4 (0.46) CYP3A4MAPK1CYP2A6AHRTDP1
SCHEMBL11025486 0.74
SCHEMBL11681212 0.72 CYP3A4 (0.35) CYP3A4MAPK1CYP2A6AHRTSHR
SCHEMBL25929030 0.72 CYP3A4 (0.35) CYP3A4MAPK1CYP2A6AHR
Hydrochloric Acid SCHEMBL8656201 0.70 CYP3A4 (0.33) CYP3A4MAPK1CYP2A6TSHR
SCHEMBL2159908 0.70 IDO1 (0.39) CYP3A4MAPK1CYP2A6AHRTDP1
SCHEMBL28685336 0.70 IDO1 (0.39) CYP3A4MAPK1CYP2A6AHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090286183-A1 TRULY PROCESSLESS LITHOGRAPHIC PRINTING PLATE PRECURSOR Yu, Yisong (CA) 2009-11-19 US disclosed