SCHEMBL25929260

SCHEMBL25929260

Oc1ccc(C2CCC(C3CCC(CC4CC4)CC3)CC2)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 5/20 0.32
ESR1 P03372 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29322541 0.95 DRD1 (0.35) OPRL1ESR1CYP3A4CYP2C9ESR2
SCHEMBL12223362 0.90 OPRL1 (0.36) OPRL1ESR2
SCHEMBL24203140 0.90 FEN1 (0.33)
SCHEMBL12994044 0.89 OPRL1 (0.39) OPRL1ESR1CYP3A4CYP2C9ESR2
SCHEMBL15725361 0.88 TRPV3 (0.32) OPRL1
SCHEMBL18641711 0.88 TRPV3 (0.32) OPRL1
SCHEMBL3269921 0.85 CYP2C9 (0.40) OPRL1CYP2C9
SCHEMBL8077590 0.85 CYP2C9 (0.40) OPRL1CYP2C9
SCHEMBL29322497 0.85 FEN1 (0.37)
SCHEMBL25929172 0.85 FEN1 (0.35) OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4056667-B1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-08-02 EP disclosed