Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493393 | 1.00 | AR (0.41) | ARITGB3ITGA2BHRH2HRH1 | |
| SCHEMBL30493385 | 0.87 | AR (0.41) | AR | |
| SCHEMBL25329631 | 0.87 | AR (0.43) | ARHRH2HRH1HRH3 | |
| SCHEMBL25931248 | 0.87 | AR (0.41) | AR | |
| SCHEMBL25329565 | 0.86 | AR (0.42) | AR | |
| SCHEMBL31131387 | 0.86 | AR (0.42) | AR | |
| SCHEMBL25931177 | 0.86 | AR (0.42) | AR | |
| SCHEMBL25330085 | 0.85 | AR (0.41) | AR | |
| SCHEMBL25330466 | 0.85 | AR (0.41) | AR | |
| SCHEMBL25328831 | 0.85 | AR (0.44) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |