Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25929486 | 0.90 | GPR119 (0.51) | ARFAAH | |
| SCHEMBL30493264 | 0.87 | GPR119 (0.48) | ARCHRM2CHRM1CHRM5FAAH | |
| SCHEMBL30493393 | 0.86 | AR (0.41) | AR | |
| SCHEMBL25929504 | 0.86 | AR (0.41) | AR | |
| SCHEMBL25931248 | 0.85 | AR (0.41) | AR | |
| SCHEMBL30493385 | 0.85 | AR (0.41) | AR | |
| SCHEMBL25328831 | 0.84 | AR (0.44) | AR | |
| SCHEMBL31131387 | 0.83 | AR (0.42) | AR | |
| SCHEMBL25931177 | 0.83 | AR (0.42) | AR | |
| SCHEMBL25330625 | 0.83 | AR (0.47) | ARCHRM2CHRM1CHRM5SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |