Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75805 | 0.90 | ALDH1A1 (0.56) | ALDH1A1MAPTPOLBTDP1RAB9A | |
| SCHEMBL30700389 | 0.90 | ALDH1A1 (0.56) | ALDH1A1MAPTPOLBTDP1RAB9A | |
| Hydrochloric Acid SCHEMBL5434602 | 0.89 | ALDH1A1 (0.55) | ALDH1A1MAPTPOLBTDP1RAB9A | |
| SCHEMBL29832698 | 0.82 | SMN1; SMN2 (0.62) | ALDH1A1POLBTDP1RAB9ASMN1; SMN2 | |
| SCHEMBL22612137 | 0.82 | CHRM2 (0.51) | ALDH1A1MAPTPOLBTDP1RAB9A | |
| SCHEMBL7712013 | 0.81 | MAPT (0.60) | ALDH1A1MAPTPOLBTDP1RAB9A | |
| SCHEMBL31215205 | 0.81 | MAPT (0.60) | ALDH1A1MAPTPOLBTDP1RAB9A | |
| SCHEMBL22747356 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPTPOLBTDP1RAB9A | |
| Hydrochloric Acid SCHEMBL16585744 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1MAPTPOLBTDP1RAB9A | |
| SCHEMBL31215234 | 0.78 | PPID (0.64) | ALDH1A1RAB9ASMN1; SMN2ALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011138266-A1 | INDOLIZINE AND IMIDAZOPYRIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | EVOTEC AG (DE) | 2011-11-10 | — | — | WO | disclosed |