Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.44 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25931211 | 0.81 | DDB1 (0.54) | CRBNDDB1 | |
| SCHEMBL20231717 | 0.80 | CRBN (0.45) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL20046865 | 0.76 | CRBN (0.47) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL27099145 | 0.70 | CRBN (0.54) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL20423189 | 0.70 | CRBN (0.48) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL31131376 | 0.70 | IKZF2 (0.54) | CRBNDDB1IKZF3 | |
| SCHEMBL20231404 | 0.70 | IKZF2 (0.54) | CRBNDDB1IKZF3 | |
| SCHEMBL31073090 | 0.69 | CRBN (0.39) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL21477243 | 0.69 | CRBN (0.51) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL26147530 | 0.69 | CRBN (0.43) | CRBNDDB1IKZF3ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574821-A | Compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2024-08-30 | — | — | CN | disclosed |
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |