Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 12/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 12/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20234368 | 0.84 | DDB1 (0.51) | DDB1CRBNGPR119SUV39H2 | |
| SCHEMBL19586987 | 0.82 | DDB1 (0.60) | DDB1CRBNMAP4K4GPR119CKS1B | |
| SCHEMBL30493301 | 0.81 | CRBN (0.49) | DDB1CRBNGPR119SUV39H2 | |
| SCHEMBL25931222 | 0.81 | CRBN (0.44) | DDB1CRBN | |
| SCHEMBL22006726 | 0.79 | DDB1 (0.54) | DDB1CRBN | |
| SCHEMBL31073337 | 0.78 | DDB1 (0.42) | DDB1CRBN | |
| SCHEMBL20423330 | 0.77 | DDB1 (0.56) | DDB1CRBNGPR119 | |
| SCHEMBL20234864 | 0.76 | CRBN (0.55) | DDB1CRBNMAP4K4GPR119 | |
| SCHEMBL30612684 | 0.76 | CRBN (0.55) | DDB1CRBNMAP4K4GPR119 | |
| SCHEMBL31073198 | 0.75 | DDB1 (0.43) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |