SCHEMBL259316

SCHEMBL259316

[CH]=C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5685262 0.77
SCHEMBL2004227 0.72
SCHEMBL779165 0.72
SCHEMBL18632299 0.72
SCHEMBL2065292 0.72
SCHEMBL27777048 0.71
SCHEMBL82518 0.71
SCHEMBL43134 0.71
SCHEMBL8059059 0.65
SCHEMBL776828 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2582 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113402361-A Gem difluoro vinyl transfer reagent and preparation method thereof 清华大学 2021-09-17 CN claimed
CN-112574269-A Purine nucleoside compound and application thereof 中国科学院上海药物研究所 2021-03-30 CN claimed
CN-111848612-A Compound containing fused heterocyclic structure, preparation method and application thereof, and bactericide 华中师范大学 2020-10-30 CN claimed
US-20200085754-A1 Prolonged Release Formulations Comprising an 2-Oxo-1-Pyrrolidine Derivative UCB Biophama SPRL (BE) 2020-03-19 US claimed
US-20190142759-A1 Prolonged Release Formulations Comprising an 2-Oxo-1-Pyrrolidine Derivative UCB PHARMA, S.A. (BE) 2019-05-16 US claimed
US-10081601-B2 Glucocerebrosidase modulators and uses thereof ALECTOS THERAPEUTICS INC. (CA) 2018-09-25 US claimed
EP-3055313-B1 CYCLIC THIENOURACIL CARBOXAMIDE AND ITS USE Bayer Pharma AG (DE) 2017-11-22 EP claimed
US-9796680-B2 Glucocerebrosidase modulators and uses thereof ALECTOS THERAPEUTICS INC. (CA) 2017-10-24 US claimed
US-20170145029-A1 CYCLIC THIENOURACIL-CARBOXAMIDES AND USE THEREOF Bayer Pharma AG (DE) 2017-05-25 US claimed
US-20170029379-A1 GLUCOCEREBROSIDASE MODULATORS AND USES THEREOF ALECTOS THERAPEUTICS INC. (CA) 2017-02-02 US claimed
WO-1994006777-A1 HETEROCYCLIC COMPOUNDS WIHT PARASITICAL ACTIVITY ZENECA LIMITED (GB) 1994-03-31 WO claimed
WO-1994006783-A1 BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES ZENECA LIMITED (GB) 1994-03-31 WO claimed
EP-0585063-A1 Controlling agent for fabric pest insects SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-03-02 EP claimed
WO-1994002470-A1 PESTICIDAL PYRIMIDINE COMPOUNDS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1994-02-03 WO claimed
US-5049551-A Antitumor UBE INDUSTRIES, LTD. (JP) 1991-09-17 US claimed
EP-0400610-A1 5-Fluorouracil derivatives UBE INDUSTRIES, LTD. (JP) 1990-12-05 EP claimed
EP-0184308-B1 PROCESS FOR PREPARING MILBEMYCIN DERIVATIVES AND CERTAIN NOVEL COMPOUNDS EMPLOYED THEREIN SANKYO COMPANY LIMITED (JP) 1989-12-27 EP claimed
EP-0184308-A1 Process for preparing milbemycin derivatives and certain novel compounds employed therein SANKYO COMPANY LIMITED (JP) 1986-06-11 EP claimed
EP-0002077-B1 ESTERS OF SUBSTITUTED CYCLOPROPANECARBOXYLIC ACIDS AND PROCESS FOR THE PREPARATION THEREOF SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1981-09-02 EP claimed
EP-0002077-A1 Esters of substituted cyclopropanecarboxylic acids and process for the preparation thereof SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1979-05-30 EP claimed