SCHEMBL259323

SCHEMBL259323

CC1(C)CCCC(C)(C)N1ON[O]

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7741916 0.90
SCHEMBL28568833 0.76 TSHR (0.36) TSHRNFKB1CYP2C19
SCHEMBL25270882 0.76 TSHR (0.40) TSHRNFKB1CYP2C19
SCHEMBL11553274 0.75 GAA (0.40)
SCHEMBL27522393 0.74 TSHR (0.35) TSHRNFKB1CYP2C19
SCHEMBL6678762 0.73 GAA (0.30)
SCHEMBL1305578 0.73 TSHR (0.33) TSHRNFKB1CYP2C19
SCHEMBL4442630 0.71 HDAC8 (0.34) TSHRNFKB1CYP2C19
SCHEMBL19463652 0.71 TSHR (0.34) TSHRNFKB1CYP2C19
SCHEMBL4747481 0.70 TSHR (0.32) TSHRNFKB1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11225584-B2 Adhesion promoter system, and method of producing the same DOW GLOBAL TECHNOLOGIES LLC (US) 2022-01-18 US disclosed
EP-3312248-B1 ADHESION PROMOTER SYSTEM, AND METHOD OF PRODUCING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2020-10-14 EP disclosed
US-10618991-B2 Reprocessable cross-linked network polymers with alkoxyamine dynamic covalent bonds NORTHWESTERN UNIVERSITY (US) 2020-04-14 US disclosed
EP-3312248-A1 ADHESION PROMOTER SYSTEM, AND METHOD OF PRODUCING THE SAME Dow Global Technologies Llc (US) 2018-04-25 EP disclosed
EP-2569382-B1 ADHESION PROMOTER SYSTEM, AND METHOD OF PRODUCING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2018-01-17 EP disclosed
EP-2569374-B1 ADHESION PROMOTER SYSTEM, AND METHOD OF PRODUCING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2017-08-23 EP disclosed
WO-2017053803-A1 REPROCESSABLE CROSS-LINKED NETWORK POLYMERS WITH ALKOXYAMINE DYNAMIC COVALENT BONDS NORTHWESTERN UNIVERSITY (US) 2017-03-30 WO disclosed
US-20170081449-A1 Reprocessable Cross-linked Network Polymers with Alkoxyamine Dynamic Covalent Bonds NORTHWESTERN UNIVERSITY 2017-03-23 US disclosed
US-8987410-B2 Terminal unsaturated, glycidol-based macromonomers, polymers obtainable therefrom, preparation and use BYK-CHEMIE GMBH (DE) 2015-03-24 US disclosed
EP-2443170-B1 TERMINAL UNSATURATED, GLYCIDOL BASED MACROMONOMERS, POLYMERS OBTAINABLE THEREFROM, PRODUCTION AND USE THEREOF BYK CHEMIE GMBH (DE) 2013-04-03 EP disclosed
EP-1802316-B1 PURINE DERIVATIVES AND METHODS OF USE THEREOF INOTEK PHARMACEUTICALS CORP (US) 2011-11-02 EP disclosed
US-20110059915-A1 PURINE DERIVATIVES AND METHODS OF USE THEREOF INOTEK PHARMACEUTICALS CORPORATION (US) 2011-03-10 US disclosed
EP-2264082-A1 Terminal unsaturated glycidol-based marcomonomers, polymers obtained from them, manufacture and use BYK-Chemie GmbH (DE) 2010-12-22 EP disclosed
EP-1996020-A2 PURINE COMPOUNDS AND METHODS OF USE THEREOF Inotek Pharmaceuticals Corporation (US) 2008-12-03 EP disclosed
US-20070238694-A1 Purine compounds and methods of use thereof INOTEK PHARMACEUTICALS CORPORATION (US) 2007-10-11 US disclosed
WO-2007111954-A2 PURINE COMPOUNDS AND METHODS OF USE THEREOF INOTEK PHAMACEUTICALS CORPORATION (US) 2007-10-04 WO disclosed
EP-1802316-A2 PURINE DERIVATIVES AND METHODS OF USE THEREOF Inotek Pharmaceuticals Corporation (US) 2007-07-04 EP disclosed
WO-2006034190-A2 PURINE DERIVATIVES AND METHODS OF USE THEREOF INOTEK PHARMACEUTICALS CORPORATION (US) 2006-03-30 WO disclosed
US-6787621-B2 USING DIARYLETHENE MONOMERS FOR MAKING PHOTOCHROMIC POLYMERIZABLE THIN FILM KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2004-09-07 US disclosed
US-20030130456-A1 Vinyl group-containing diarylethene and polymer thereof having excellent optical properties KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 2003-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238694-A1 Purine compounds and methods of use thereof PNP, ADORA2A, P2RY1 TSHR 4003/4885NFKB1 999/4885CYP2C19 2147/4885
US-20110059915-A1 PURINE DERIVATIVES AND METHODS OF USE THEREOF PNP, NUDT1, HPRT1 TSHR 4281/4885NFKB1 918/4885CYP2C19 1928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.