Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | LIPE | Q05469 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.32 |
| ▸ | ADAM33 | Q9BZ11 | 1/20 | 0.32 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25326350 | 0.93 | MGLL (0.38) | MGLLEPHX2HCRTR1KDM4EABL1 | |
| SCHEMBL25325658 | 0.84 | MGLL (0.45) | MGLLEPHX2HCRTR1LIPEKDM4E | |
| SCHEMBL25327491 | 0.84 | MGLL (0.40) | MGLLEPHX2HCRTR1ADAM10MMP1 | |
| SCHEMBL25324097 | 0.83 | MGLL (0.42) | MGLLEPHX2HCRTR1LIPE | |
| SCHEMBL25326703 | 0.81 | MGLL (0.41) | MGLLEPHX2HCRTR1LIPEADAM10 | |
| SCHEMBL25324506 | 0.81 | MGLL (0.40) | MGLLEPHX2HCRTR1LIPEADAM10 | |
| SCHEMBL25325243 | 0.80 | MGLL (0.37) | MGLLEPHX2HCRTR1LIPEADAM10 | |
| SCHEMBL25324110 | 0.79 | MGLL (0.39) | MGLLHCRTR1ADAM10MMP1MMP2 | |
| SCHEMBL31532366 | 0.79 | MGLL (0.38) | MGLL | |
| SCHEMBL30700373 | 0.78 | MGLL (0.43) | MGLLEPHX2HCRTR1LIPEPAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |