Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28852509 | 0.97 | TSHR (0.43) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL5504190 | 0.87 | TSHR (0.41) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL10382473 | 0.87 | TSHR (0.43) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL11310728 | 0.84 | TSHR (0.41) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL515831 | 0.82 | TSHR (0.39) | TSHRHPGDTHRBALDH1A1 | |
| SCHEMBL25933341 | 0.81 | ZDHHC7 (0.38) | ZDHHC20ZDHHC2ZDHHC7ABCB1FAAH | |
| SCHEMBL769930 | 0.81 | TSHR (0.47) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| SCHEMBL31742398 | 0.80 | TSHR (0.50) | TSHRHPGDTHRBZDHHC20ZDHHC2 | |
| Hydrochloric Acid SCHEMBL28283677 | 0.80 | TSHR (0.38) | TSHRHPGDTHRBALDH1A1 | |
| SCHEMBL160397 | 0.80 | TSHR (0.50) | TSHRHPGDTHRBZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242548-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242548-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | KRAS, HRAS, NRAS | TSHR 4752/4885HPGD 1795/4885THRB 3669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.