SCHEMBL25933341

SCHEMBL25933341

C/C=C/C(=O)OC(CCCCC)NC

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.38
FAAH O00519 5/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
ATM Q13315 1/20 0.35
SMPD1 P17405 3/20 0.35
GPR84 Q9NQS5 3/20 0.34
FFAR1 O14842 1/20 0.34
CA1 P00915 1/20 0.34
HCAR2 Q8TDS4 2/20 0.34
MAPT P10636 1/20 0.33
ABCB1 P08183 1/20 0.33
LCK P06239 1/20 0.33
PPARD Q03181 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28283798 0.82 SMPD1 (0.43) ZDHHC7FAAHATMSMPD1GPR84
SCHEMBL25933337 0.81 TSHR (0.46) ZDHHC7FAAHCNR1CNR2GPR84
SCHEMBL11455121 0.79 GPR84 (0.40) ZDHHC7ATMSMPD1GPR84FFAR1
Hydrochloric Acid SCHEMBL28852509 0.79 TSHR (0.43) ZDHHC7FAAHCNR1CNR2GPR84
SCHEMBL23522264 0.78 FAAH (0.51) FAAHCNR1CNR2SMPD1GPR84
SCHEMBL1070568 0.78 PRKCA (0.40) ZDHHC7ATMSMPD1GPR84FFAR1
SCHEMBL27703277 0.78 FAAH (0.51) FAAHCNR1CNR2SMPD1GPR84
SCHEMBL1070567 0.78 PRKCA (0.40) ZDHHC7ATMSMPD1GPR84FFAR1
SCHEMBL28592392 0.76 CA2 (0.38) ZDHHC7FAAHATMCA1HCAR2
SCHEMBL27992319 0.75 HCAR2 (0.37) ZDHHC7FAAHATMSMPD1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242548-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242548-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER KRAS, HRAS, NRAS ZDHHC7 815/4885FAAH 3508/4885CNR1 3237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.