Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.61 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.55 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | CCR3 | P51677 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4232026 | 0.86 | SSTR5 (0.53) | HRH3SRD5A1SSTR5SRD5A2ADRB2 | |
| SCHEMBL25933643 | 0.86 | HRH3 (0.58) | HRH3ADRB2MEN1KMT2ALMNA | |
| SCHEMBL18361356 | 0.84 | HRH1 (0.66) | SRD5A1SSTR5SRD5A2LMNAALDH1A1 | |
| SCHEMBL18361240 | 0.83 | SRD5A1 (0.51) | SRD5A1SSTR5SRD5A2ADRB2MEN1 | |
| SCHEMBL3458790 | 0.83 | SRD5A1 (0.59) | HRH3SRD5A1SRD5A2MEN1KMT2A | |
| SCHEMBL4232659 | 0.82 | SRD5A1 (0.50) | SRD5A1SSTR5SRD5A2ADRB2MEN1 | |
| SCHEMBL24214132 | 0.82 | EPHX2 (0.53) | SRD5A1SSTR5SRD5A2ADRB2LMNA | |
| SCHEMBL4237889 | 0.82 | OPRK1 (0.65) | HRH3SRD5A1SSTR5ADRB2MEN1 | |
| SCHEMBL4237909 | 0.81 | CHRM2 (0.52) | HRH3SRD5A1SSTR5SRD5A2LMNA | |
| SCHEMBL8391744 | 0.81 | HRH3 (0.67) | HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250106-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250106-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | HRH3 1666/4885SRD5A1 3903/4885SSTR5 3764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.