Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 10/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15349057 | 0.88 | F2RL3 (0.44) | F2RL3SLC6A4SLC6A3ICMTHTR2C | |
| SCHEMBL25933735 | 0.86 | F2RL3 (0.42) | F2RL3SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL15349224 | 0.83 | F2RL3 (0.46) | F2RL3SLC6A4SLC6A3ICMTSLC6A2 | |
| SCHEMBL15349123 | 0.74 | F2RL3 (0.42) | F2RL3 | |
| SCHEMBL15349106 | 0.72 | F2RL3 (0.39) | F2RL3 | |
| SCHEMBL15348977 | 0.71 | F2RL3 (0.49) | F2RL3ICMT | |
| SCHEMBL15057062 | 0.69 | SLC6A4 (0.71) | SLC6A4SLC6A3ICMTDPP4DPP9 | |
| SCHEMBL25933755 | 0.69 | ICMT (0.38) | F2RL3SLC6A4SLC6A3ICMTSLC6A2 | |
| Hydrochloric Acid SCHEMBL29428954 | 0.68 | SLC6A4 (0.69) | SLC6A4SLC6A3ICMTHTR2CHTR2A | |
| SCHEMBL5646704 | 0.68 | ROCK1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242535-A1 | IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION | BRISTOL MYERS SQUIBB CO (US) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242535-A1 | IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION | F2RL3, F2R, TMPRSS4 | F2RL3 1/4885SLC6A4 413/4885SLC6A3 1513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.