Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 17/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493231 | 0.91 | AR (0.45) | ARBRD4KCNH2 | |
| SCHEMBL25929486 | 0.89 | GPR119 (0.51) | ARRET | |
| SCHEMBL25934240 | 0.88 | AR (0.49) | ARRET | |
| SCHEMBL25934165 | 0.88 | AR (0.50) | AR | |
| SCHEMBL25437610 | 0.87 | AR (0.46) | AR | |
| SCHEMBL25330426 | 0.87 | AR (0.46) | ARRET | |
| SCHEMBL25330446 | 0.86 | AR (0.43) | ARRET | |
| SCHEMBL30493235 | 0.86 | AR (0.43) | ARRET | |
| SCHEMBL30493283 | 0.86 | HRH2 (0.45) | KCNH2RET | |
| SCHEMBL30493264 | 0.85 | GPR119 (0.48) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466260-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | Astrazeneca AB (SE) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |