Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 15/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.33 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31701106 | 0.92 | CRBN (0.52) | CRBNDDB1IRAK4IKZF1IKZF2 | |
| SCHEMBL26098283 | 0.91 | DDB1 (0.46) | CRBNDDB1IRAK4IKZF1IKZF2 | |
| SCHEMBL26098278 | 0.91 | DDB1 (0.46) | CRBNDDB1IRAK4IKZF1IKZF2 | |
| SCHEMBL21997445 | 0.90 | DDB1 (0.53) | CRBNDDB1USP2CYP2D6IKZF3 | |
| SCHEMBL31700697 | 0.88 | DDB1 (0.51) | CRBNDDB1IRAK4IKZF1IKZF2 | |
| SCHEMBL21996775 | 0.87 | CRBN (0.53) | CRBNDDB1USP2CYP2D6IKZF3 | |
| Trifluoroacetic Acid SCHEMBL30392458 | 0.86 | CRBN (0.41) | CRBNDDB1IRAK4IKZF1IKZF2 | |
| SCHEMBL23842385 | 0.85 | DDB1 (0.47) | CRBNDDB1 | |
| SCHEMBL21070862 | 0.85 | CRBN (0.52) | CRBNDDB1IKZF2IKZF3 | |
| SCHEMBL26634965 | 0.85 | CRBN (0.52) | CRBNDDB1IKZF1IKZF2IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109892-A1 | COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |