Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 12/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 12/20 | 0.51 |
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.36 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31701106 | 0.94 | CRBN (0.52) | DDB1CRBNIKZF2IKZF1IRAK4 | |
| SCHEMBL21997901 | 0.94 | CRBN (0.57) | DDB1CRBN | |
| Hydrochloric Acid SCHEMBL31134510 | 0.93 | CRBN (0.56) | DDB1CRBNHTR6 | |
| SCHEMBL21070862 | 0.90 | CRBN (0.52) | DDB1CRBNIKZF2 | |
| SCHEMBL26634965 | 0.90 | CRBN (0.52) | DDB1CRBNIKZF2IKZF1 | |
| Hydrochloric Acid SCHEMBL30043421 | 0.90 | CRBN (0.51) | DDB1CRBNIKZF2 | |
| SCHEMBL26635024 | 0.89 | DDB1 (0.52) | DDB1CRBNIKZF2 | |
| SCHEMBL25934140 | 0.88 | CRBN (0.47) | DDB1CRBNIKZF2IKZF1IRAK4 | |
| SCHEMBL25338108 | 0.87 | DDB1 (0.52) | DDB1CRBNIKZF2IKZF1 | |
| SCHEMBL26635128 | 0.86 | CRBN (0.48) | DDB1CRBNIKZF2IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014147-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-20250325677-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250320206-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325677-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | DDB1 3966/4885CRBN 1627/4885IKZF2 28/4885 |
| US-20260014147-A1 | STAT6 DEGRADERS | STAT6, NCOR1, CBR1 | DDB1 3708/4885CRBN 133/4885IKZF2 530/4885 |
| US-20250320206-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | DDB1 3966/4885CRBN 1627/4885IKZF2 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.