Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 14/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GRAMD1A | Q96CP6 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25934728 | 0.88 | CRBN (0.48) | CRBNDDB1ESR2 | |
| SCHEMBL25339479 | 0.82 | DDB1 (0.43) | CRBNDDB1 | |
| SCHEMBL25339007 | 0.82 | DDB1 (0.43) | CRBNDDB1 | |
| SCHEMBL25934808 | 0.80 | CRBN (0.49) | CRBNDDB1ESR2 | |
| SCHEMBL31161601 | 0.80 | DDB1 (0.40) | CRBNDDB1 | |
| SCHEMBL25339527 | 0.79 | DDB1 (0.49) | CRBNDDB1 | |
| SCHEMBL26099800 | 0.77 | CRBN (0.54) | CRBNDDB1 | |
| SCHEMBL31211920 | 0.77 | DDB1 (0.44) | CRBNDDB1 | |
| SCHEMBL31211791 | 0.77 | DDB1 (0.44) | CRBNDDB1 | |
| SCHEMBL30543629 | 0.77 | DDB1 (0.44) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109892-A1 | COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |